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PBP10

Product Specifications

CAS Number

794466-43-6

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

Smiles

C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)[C@H](C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)(=O)C2=C(C=3C4=C([O+]=C5C3C=CC(N(CC)CC)=C5)C=C(N(CC)CC)C=C4)C=CC=C2

Molecular Formula

C84H126N24O15

Molecular Weight

1712.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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