Pep2m, myristoylated

Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.

[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)C)=O)CC(N)=O)=O)CCCCN)=O)C)=O)[C@H](C)C)=O)CCCCN)=O)CCSC)=O)(NC([C@@H](NC(CCCCCCCCCCCCC)=O)CCCCN)=O)CCCNC(=N)N