Pep2-EVKI
Product Specifications
CAS Number
1315378-67-6
Target
PKC
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling
Bioactivity
Pep2-EVKI is an inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluA2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1) . Does not affect binding of GluA2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD) .
Smiles
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O
Molecular Formula
C62H95N13O19
Molecular Weight
1326.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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