Pep2-AVKI
Product Specifications
CAS Number
1315378-69-8
Target
IGluR
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Bioactivity
Pep2-AVKI is an inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluA2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1) . Does not affect binding of GluA2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD) .
Smiles
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O
Molecular Formula
C60H93N13O17
Molecular Weight
1268.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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