Ac-RYYRIK-NH2 acetate

Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ (noc/OFQ) receptors, affecting spontaneous locomotor activity. Ac-RYYRIK-NH2 acetate is a partial agonist on ORL1 transfected in CHO cells, antagonizes the stimulation of [35S]-GTPgammaS binding to G proteins by noc/OFQ in membranes and sections of rat brain.

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