L-R4W2

Product Specifications

CAS Number

206350-79-0

Target

TRP/TRPV Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 ?M) ; blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.

Smiles

C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C=3C=4C(NC3)=CC=CC4

Molecular Formula

C46H71N21O6

Molecular Weight

1014.2

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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