[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P acetate

[D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P acetate ([D-Arg1, D-Phe5, D-Trp7,9, Leu11]-Substance P acetate (96736-12-8 free base) ) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM) ; diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.

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