Lys-[Des-Arg9]Bradykinin

Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively) . Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin.

C(=O)([C@H]1N(C([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(=N)N)=O)CCC1)N2[C@H](C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(=O)N4[C@H](C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)CCC4)CO)=O)=O)=O)CCC2