Sar-[D-Phe8]-des-Arg9-Bradykinin
Product Specifications
CAS Number
126959-88-4
Target
Bradykinin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic activity in vivo.
Smiles
C(=O)([C@H]1N(C([C@@H](NC(CNC)=O)CCCNC(=N)N)=O)CCC1)N2[C@H](C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(=O)N4[C@H](C(N[C@H](CC5=CC=CC=C5)C(O)=O)=O)CCC4)CO)=O)=O)=O)CCC2
Molecular Formula
C47H66N12O11
Molecular Weight
975.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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