[D-Phe12, Leu14]-Bombesin
Product Specifications
CAS Number
108437-88-3
Target
Bombesin Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 ?M. Inhibits amylase release in vitro (IC50 = 4 ?M) and attenuates bombesin-mediated suppression of food intake in vivo.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCC(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CC(N)=O)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)[C@@H](C)C)=O)C)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C77H113F3N22O20
Molecular Weight
1724.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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