CALP1 acetate

Product Specifications

Target

CaMK|||Calcium Channel

Related Pathways

Metabolism|||Neuroscience|||Membrane transporter/Ion channel

Purity

0.9963

Bioactivity

CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity.

Smiles

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