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CALP1 acetate

Product Specifications

Target

CaMK|||Calcium Channel

Related Pathways

Metabolism|||Neuroscience|||Membrane transporter/Ion channel

Purity

0.9963

Bioactivity

CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity.

Smiles

CC[C@]([H])(C)[C@@]([H])(/C(O)=N/[C@@]([H])([C@@]([H])(C)O)/C(O)=N/[C@@]([H])(C(C)C)/C(O)=N/[C@@]([H])(CC(C)C)/C(O)=N/[C@@]([H])(C(C)C)/C(O)=N/[C@@]([H])(CCCCN)C(O)=O)/N=C([C@]([H])(C)/N=C([C@]([H])(C(C)C)N)\O)\O.CC(O)=O

Molecular Formula

C42H79N9O12

Molecular Weight

902.13

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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