CALP2 acetate (261969-04-4 free base)
Product Specifications
Target
CaMK|||PDE
Related Pathways
Metabolism|||Neuroscience
Purity
0.9743
Bioactivity
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM. CALP2 acetate potently inhibits of adhesion and degranulation. CALP2 acetate is also a strong activator of alveolar macrophages. CALP2 acetate inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations.
Smiles
CC(C)[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](Cc1ccccc1)C(NCC(N[C@@H](C(C)C)C(NCC(N[C@@H](Cc1ccccc1)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](Cc1ccccc1)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N
Molecular Formula
C68H104N14O13S
Molecular Weight
1357.7
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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