FSLLRY-NH2
Product Specifications
CAS Number
245329-02-6
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
Smiles
[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)(C(N[C@@H](CC2=CC=C(O)C=C2)C(N)=O)=O)CCCNC(=N)N
Molecular Formula
C39H60N10O8
Molecular Weight
796.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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