G-Protein antagonist peptide

Substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.

C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCSC)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC(=O)[C@H]5NC(=O)CC5)CCC(N)=O)=O)=O)CC6=CC=CC=C6)=O)C=7C=8C(NC7)=CC=CC8