HS024
Product Specifications
CAS Number
212370-59-7
Target
Melanocortin Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
>99.99%
Bioactivity
HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively) . Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)[C@H](CC6=CN=CN6)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCC)NC(=O)[C@@H](NC(C)=O)CSSC[C@@H](C(N)=O)NC(=O)CNC3=O
Molecular Formula
C58H79N19O10S2
Molecular Weight
1266.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
B2553-30-FITC 100 µL
Bone Morphogenic Protein 6 (BMP6, vgr-1, Vegetal Related, DVR-6, Decapentaplegic Vegetal Related) (FITC) discontinued
Sign In for Pricing
View Details 
252549-HRP 100 µL
TET1 (tet Oncogene 1, CXXC6, FLJ10839, FLJ41442, KIAA1676, LCX, bA119F7.1) (HRP)
Sign In for Pricing
View Details 
411620-01 5 mg
10-Desmethoxy Tetrahyrocolchicoside β-D-Glucopyranosyl Tetraacetate
Sign In for Pricing
View Details 411620-02 10 mg
10-Desmethoxy Tetrahyrocolchicoside β-D-Glucopyranosyl Tetraacetate
Sign In for Pricing
View Details T9237-08-ML405 100 µL
Tyrosine Hydroxylase, phosphorylated (Ser31) (TH, TYH, Tyrosine 3 Hydroxylase, Tyrosine 3 Monooxygenase) (MaxLight 405) discontinued
Sign In for Pricing
View Details