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MLCK inhibitor peptide 18

Product Specifications

CAS Number

224579-74-2

Target

Autophagy, Myosin, CaMK

Related Pathways

Neuroscience, Cytoskeletal Signaling, Autophagy

Bioactivity

Selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM) . Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.

Smiles

[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O

Molecular Formula

C60H105N23O11

Molecular Weight

1324.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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