MCL0020
Product Specifications
CAS Number
475498-26-1
Target
Melanocortin Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9918
Bioactivity
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115, and >10,000 nM at MC4, MC3, and MC1 receptors, respectively) . It significantly reverses stress-induced anorexia without affecting food intake in free-feeding rats and exhibits anxiolytic-like activity in vivo.
Smiles
C([C@H](C(N[C@H](C(N[C@@H](CC1=CC2=C(C=C1)C=CC=C2)C(N)=O)=O)CCCNC(=N)N)=O)NC(C)=O)C3=CC4=C(C=C3)C=CC=C4
Molecular Formula
C34H39N7O4
Molecular Weight
609.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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