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MCL0020

Product Specifications

CAS Number

475498-26-1

Target

Melanocortin Receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Purity

0.9918

Bioactivity

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115, and >10,000 nM at MC4, MC3, and MC1 receptors, respectively) . It significantly reverses stress-induced anorexia without affecting food intake in free-feeding rats and exhibits anxiolytic-like activity in vivo.

Smiles

C([C@H](C(N[C@H](C(N[C@@H](CC1=CC2=C(C=C1)C=CC=C2)C(N)=O)=O)CCCNC(=N)N)=O)NC(C)=O)C3=CC4=C(C=C3)C=CC=C4

Molecular Formula

C34H39N7O4

Molecular Weight

609.72

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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