Orphanin FQ (1-11) acetate (178249-41-7 free base)

Orphanin FQ (1-11) acetate (178249-41-7 free base) is a peptide fragment containing amino acids 1-11 of Nociceptin. Orphanin FQ (1-11) acetate (178249-41-7 free base) is a potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM) and displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM) . Orphanin FQ (1-11) acetate (178249-41-7 free base) displays analgesic properties in CD-1 mice.

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