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HSDVHK-NH2

Product Specifications

CAS Number

848644-86-0

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM) . Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.

Smiles

CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(N)=O

Molecular Formula

C30H48N12O9

Molecular Weight

720.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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