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Histatin 5

Product Specifications

CAS Number

115966-68-2

Target

MMP

Related Pathways

Proteases/Proteasome

Bioactivity

Histatin 5, a human basic salivary peptide with strong fungicidal properties in vitro, inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.

Smiles

[C@@H](CC1=CN=CN1)(NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@H](CC4=CN=CN4)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC6=CN=CN6)NC([C@@H](NC([C@H](CC(O)=O)N)=O)CO)=O)=O)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@@H](CC8=CN=CN8)C(N[C@H](C(N[C@@H](CC9=CN=CN9)C(N[C@H](C(NCC(N[C@@H](CC%10=CC=C(O)C=C%10)C(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CO)=O)=O)=O)CCCCN)=O)CCC(O)=O)=O

Molecular Formula

C133H195N51O33

Molecular Weight

3036.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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