Hsp70-derived octapeptide

A group of tetratricopeptide repeat (TPR) -containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70) . In the present study, the effect of the TPR-containing proteins, including the C-terminus of hsc70-interacting protein (CHIP), TPR1 and human glutamine-rich TPR-containing protein (hSGT), on refolding of luciferase by DnaJ and hsc70 was investigated.

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