G280-9 acetate (156761-76-1 free base)

G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.

O=C([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(C=C1)O)N)=O)CC(C)C)=O)CCC(O)=O)N2CCC[C@H]2C(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@@H](C)O)=O)C(C)C)=O)=O)=O.CC(O)=O