Ac2-26

Product Specifications

CAS Number

151988-33-9

Target

STAT, Annexin A, p38 MAPK, NF-κB, IL Receptor, Akt, PI3K

Related Pathways

GPCR/G Protein, Immunology/Inflammation, Stem Cells, NF-κB, JAK/STAT signaling, Cytoskeletal Signaling, MAPK, PI3K/Akt/mTOR signaling

Purity

0.9878

Bioactivity

Ac2-26, an annexin A1 mimetic peptide, was able to attenuate renal inflammatory injury in a diabetic mouse model through inhibition of p38MAPK/NF-κB, as well as sepsis-induced cardiomyocyte apoptosis through the LXA4/PI3K/AKT signalling pathway, and hepatic ischaemia-reperfusion injury in mice by modulating IL-22/IL-22R1/STAT3 signalling pathway.

Smiles

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