Ac2-26

Product Specifications

CAS Number

151988-33-9

Target

STAT|||Annexin A|||p38 MAPK|||NF-?B|||IL Receptor|||Akt|||PI3K

Related Pathways

GPCR/G Protein|||Immunology/Inflammation|||Stem Cells|||NF-?B|||JAK/STAT signaling|||Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling

Purity

0.9878

Bioactivity

Ac2-26, an annexin A1 mimetic peptide, was able to attenuate renal inflammatory injury in a diabetic mouse model through inhibition of p38MAPK/NF-?B, as well as sepsis-induced cardiomyocyte apoptosis through the LXA4/PI3K/AKT signalling pathway, and hepatic ischaemia-reperfusion injury in mice by modulating IL-22/IL-22R1/STAT3 signalling pathway.

Smiles

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