Etelcalcetide hydrochloride
Product Specifications
CAS Number
1334237-71-6
Target
CaSR
Related Pathways
GPCR/G Protein
Purity
>99.99%
Bioactivity
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that serves as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively reducing parathyroid hormone (PTH) levels in patients with secondary hyperparathyroidism undergoing hemodialysis.
Smiles
Cl.C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@@H](CSSC[C@H](N)C(O)=O)NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C(O)=O
Molecular Formula
C38H73N21O10S2.17/2HCl
Molecular Weight
1353.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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