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Etelcalcetide hydrochloride

Product Specifications

CAS Number

1334237-71-6

Target

CaSR

Related Pathways

GPCR/G Protein

Purity

>99.99%

Bioactivity

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that serves as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively reducing parathyroid hormone (PTH) levels in patients with secondary hyperparathyroidism undergoing hemodialysis.

Smiles

Cl.C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](C)NC(=O)[C@@H](CSSC[C@H](N)C(O)=O)NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C(O)=O

Molecular Formula

C38H73N21O10S2.17/2HCl

Molecular Weight

1353.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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