Apamin
Product Specifications
CAS Number
24345-16-2
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom) that selectively blocks Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity. This component of bee venom is strongly basic in nature.
Smiles
CC(C)CC1NC(=O)C(C)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(CCCCN)NC(=O)C2CSSCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(CSSCC(N)C(=O)NC(CC(N)=O)C(=O)N2)NC1=O)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(N)=O)C(C)O
Molecular Formula
C79H131N31O24S4
Molecular Weight
2027.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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