Urotensin I acetate (83930-33-0 Free base)

Product Specifications

Target

CRFR

Related Pathways

GPCR/G Protein

Purity

0.9973

Bioactivity

Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2? receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2? and mCRF2? receptors, respectively[1][2].

Smiles

CC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CCSC)=O)C)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C(C)C)=O)CCC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CC1=CC=C(O)C=C1)=O)CCCCN)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CC(C)C)=O)=O)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)C.O=C(C)O