Urotensin I
Product Specifications
CAS Number
83930-33-0
Target
CRFR
Related Pathways
GPCR/G Protein
Bioactivity
Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively. Urotensin-I was first isolated from the urophysis of the white sucker, and has been shown to decrease blood pressure in the rat. UI consists of 41 aa residues with an amidated C-terminus.
Molecular Formula
C210H340N62O67S2
Molecular Weight
4869.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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