Urotensin I

Product Specifications

CAS Number

83930-33-0

Target

CRFR

Related Pathways

GPCR/G Protein

Bioactivity

Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2? receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2? and mCRF2? receptors, respectively. Urotensin-I was first isolated from the urophysis of the white sucker, and has been shown to decrease blood pressure in the rat. UI consists of 41 aa residues with an amidated C-terminus.

Molecular Formula

C210H340N62O67S2

Molecular Weight

4869.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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