Fibrinopeptide A, human TFA

Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively.

OC(C(F)(F)F)=O.N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC(CNC(CNC(CNC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC(CNC([C@H](CCC(O)=O)NC(CNC([C@H](CO)NC([C@H](CC(O)=O)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O