Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP 161-180) is a 20-residue peptide that acts as a major pathogenic epitope, located in the first homologous repeat of interstitial visual pigment Binding Protein, and can induce post-uveitis (EAU) .

C([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC(CNC([C@H](CO)N)=O)=O)[C@H](CC)C)=O)CCC3)CC4=CC=C(O)C=C4)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CO)=O)=O)CC(C)C)=O)(=O)N5[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC6=CN=CN6)C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)[C@@H](C)C)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)=O)CCC5