5'-Azido-5'-deoxythymidine
Product Specifications
CAS Number
19316-85-9
Target
Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9985
Bioactivity
5'-Azido-5'-deoxythymidine is a nucleoside analog with potential anti-tuberculosis activity as an inhibitor of Mycobacterium tuberculosis monophosphate kinase (TMPKmt), an enzyme essential for DNA replication in Mycobacterium tuberculosis. 5'-Azido-5'-deoxythymidine contains an azide group in its molecular structure, which enhances its ability to inhibit reverse transcriptase, and is commonly used in the study of nucleoside metabolic pathways and related disease mechanisms.
Smiles
Cc1cn([C@H]2C[C@H](O)[C@@H](CN=[N+]=[N-])O2)c(=O)[nH]c1=O
Molecular Formula
C10H13N5O4
Molecular Weight
267.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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