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4-(6-Bromo-2-benzothiazolyl)benzenamine

Product Specifications

UNSPSC Description

4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.

Target Antigen

Amyloid-β; Oxidative Phosphorylation

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4-_6-Bromo-2-benzothiazolyl_benzenamine.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

NC1=CC=C(C2=NC3=CC=C(Br)C=C3S2)C=C1

Molecular Weight

305.19

References & Citations

[1]Klunk W, et al. Benzothiazole derivative compounds, compositions and uses. WO2004083195 A1|[2]Chen YK, et al. Apoptosis induced by 2-aryl benzothiazoles-mediated photodynamic therapy in melanomas via mitochondrial dysfunction. Chem Res Toxicol. 2014 Jul 21;27(7):1187-98.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111514/4-6-Bromo-2-benzothiazolyl-benzenamine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111514/4-6-Bromo-2-benzothiazolyl-benzenamine-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

566169-97-9

Available Sizes

Curated Selection

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