4- (6-Bromo-2-benzothiazolyl) benzenamine
4- (6-Bromo-2-benzothiazolyl) benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.
Product Specifications
CAS Number
566169-97-9
UNSPSC
12352005
Target
Amyloid-β; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-_6-Bromo-2-benzothiazolyl_benzenamine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
NC1=CC=C(C2=NC3=CC=C(Br)C=C3S2)C=C1
Molecular Formula
C13H9BrN2S
Molecular Weight
305.19
References & Citations
[1]Klunk W, et al. Benzothiazole derivative compounds, compositions and uses. WO2004083195 A1|[2]Chen YK, et al. Apoptosis induced by 2-aryl benzothiazoles-mediated photodynamic therapy in melanomas via mitochondrial dysfunction. Chem Res Toxicol. 2014 Jul 21;27 (7) :1187-98.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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