Bigelovin
Product Specifications
CAS Number
3668-14-2
Target
ROS, Autophagy, Retinoid Receptor, Apoptosis, RAR/RXR, Reactive Oxygen Species
Related Pathways
Immunology/Inflammation, Metabolism, Apoptosis, Autophagy, NF-κB
Purity
0.9972
Bioactivity
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.
Smiles
[H][C@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@@H]1C(=C)C(=O)O2
Molecular Formula
C17H20O5
Molecular Weight
304.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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