Boc-NH-C4-Br

Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[164365-88-2]

UNSPSC

12352211

Hazard Statement

H318

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-c4-br.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OC(C)(C)C)NCCCCBr

Molecular Formula

C9H18BrNO2

Molecular Weight

252.15

Precautions

H318

References & Citations

[1]Hu R, et, al. Identification of a selective BRD4 PROTAC with potent antiproliferative effects in AR-positive prostate cancer based on a dual BET/PLK1 inhibitor. Eur J Med Chem. 2022 Jan 5;227:113922.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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