Chamaejasmine
Product Specifications
CAS Number
69618-96-8
Target
ROS, Reactive Oxygen Species, Apoptosis, AMPK, Autophagy
Related Pathways
NF-κB, PI3K/Akt/mTOR signaling, Metabolism, Autophagy, Chromatin/Epigenetic, Immunology/Inflammation, Apoptosis
Bioactivity
Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate the outer mitochondrial membrane and causes cytochrome c release.
Smiles
[H][C@@]1([C@@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)cc1)[C@@]1([H])[C@@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)cc1
Molecular Formula
C30H22O10
Molecular Weight
542.496
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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