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Chamaejasmine

Product Specifications

CAS Number

69618-96-8

Target

ROS|||Reactive Oxygen Species|||Apoptosis|||AMPK|||Autophagy

Related Pathways

NF-?B|||PI3K/Akt/mTOR signaling|||Metabolism|||Autophagy|||Chromatin/Epigenetic|||Immunology/Inflammation|||Apoptosis

Bioactivity

Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate the outer mitochondrial membrane and causes cytochrome c release.

Smiles

[H][C@@]1([C@@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)cc1)[C@@]1([H])[C@@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)cc1

Molecular Formula

C30H22O10

Molecular Weight

542.496

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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