Alisol B acetate
Product Specifications
CAS Number
19865-76-0
Target
Caspase|||Apoptosis|||Akt|||PI3K
Related Pathways
Proteases/Proteasome|||Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling
Bioactivity
Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways.
Smiles
CC(C)C(=O)[C@H](C[C@@H](C)C1=C2C[C@H](O)[C@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]3(C)[C@@]2(C)CC1)OC(C)=O
Molecular Formula
C32H50O5
Molecular Weight
514.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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