Nauclefine
Product Specifications
CAS Number
57103-51-2
Target
Apoptosis, PDE
Related Pathways
Metabolism, Apoptosis
Purity
0.9992
Bioactivity
Nauclefine (Parvine) is a plant indole alkaloid natural product and induces apoptosis of diverse cancer cells via a PDE3A-SLFN12 dependent death pathway. Nauclefine binds PDE3A but does not inhibit the PDE3A's phosphodiesterase activity.
Smiles
O=C1N2C(C3=C(C=4C(N3)=CC=CC4)CC2)=CC=5C1=CN=CC5
Molecular Formula
C18H13N3O
Molecular Weight
287.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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