Isoerysenegalensein E
Product Specifications
CAS Number
478158-77-9
Bioactivity
Isoerysenegalensein E shows anti-estrogenic activity comparable to that of 4-hydroxytamoxifen, a typical estrogen receptor antagonist. It shows significant cytotoxicity against HL-60 cells, it induces apoptosis in HL-60 cells through activation of the caspase-9/caspase-3 pathway, which is triggered by mitochondrial dysfunction.
Smiles
CC(C)=CCc1c(O)c(CC(O)C(C)=C)c(O)c2c1occ(-c1ccc(O)cc1)c2=O
Molecular Formula
C25H26O6
Molecular Weight
422.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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