Icariside E4
Product Specifications
CAS Number
126253-42-7
Target
AMPK|||Liver X Receptor|||Lipid|||Fatty Acid Synthase|||Potassium Channel|||Antioxidant
Related Pathways
PI3K/Akt/mTOR signaling|||Metabolism|||Chromatin/Epigenetic|||Oxidation-Reduction|||Membrane transporter/Ion channel
Bioactivity
Icariside E4 is a natural compound derived from Ulmus minor that acts via AMPK phosphorylation and inhibition of MID1IP2 hypolipidation in HepG1 cells.Icariside E4 has anti-injurious, antioxidant, anti-Alzheimer's and anti-inflammatory effects and inhibits SREBP-1c, liver X receptor-? (LXR) and FASN in Icariside E4 is an effective candidate for the treatment of fatty liver disease and has hypolipidemic potential in HepG1 cells.
Smiles
C(O)[C@@H]1C=2C(O[C@H]1C3=CC(OC)=C(O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C=C3)=C(OC)C=C(CCCO)C2
Molecular Formula
C26H34O10
Molecular Weight
506.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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