Dehydroleucodine
Product Specifications
CAS Number
36150-07-9
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating adipocyte differentiation by modulating the PPAR? expression, which is known to play a pivotal role during adipogenesis. Dehydroleucodine may be attributed to interference with multiple targets on the level of transcription factors, such as NF-kappaB, and cytokines. Dehydroleucodine induces a TP73-dependent transcriptional regulation of multiple cell death target genes in human glioblastoma cells.
Smiles
CC1=C2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3CC1)C(=CC2=O)C
Molecular Formula
C15H16O3
Molecular Weight
244.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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