What is the catalog number for Chlorahololide D?

The catalog number for Chlorahololide D is TN5335.

What sizes are available for Chlorahololide D?

Chlorahololide D is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does Chlorahololide D come in?

Chlorahololide D is available in 4 different pack sizes.

Is Chlorahololide D in stock?

Chlorahololide D is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Chlorahololide D?

Chlorahololide D is manufactured by Molfinity.

What is the estimated delivery time for Chlorahololide D?

Estimated delivery time for Chlorahololide D is approximately 10 business day(s), depending on your location.

Chlorahololide D

Product Specifications

CAS Number

943136-39-8

Target

Bcl-2 Family, Potassium Channel, FAK

Related Pathways

Apoptosis, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Membrane transporter/Ion channel

Purity

0.9843

Bioactivity

Chlorahololide D is a natural lindane-type sesquiterpene dimer and selective potassium channel blocker that stimulates reactive oxygen species ROS levels to cause cell cycle arrest in the G2 phase, modulates Bcl-2 and Bax and FAK, thereby inhibiting MCF-7 cell growth and triggering apoptosis. Chlorahololide D inhibits tumor proliferation, migration and angiogenesis in in vivo experiments and has anti-breast cancer potential.

Smiles

C(\C(OC)=O)(/C)=C\1/[C@@]2([C@@]34[C@]([C@@]5(C)[C@]6([C@](C6)([C@](COC(/C(=C/C)/C)=O)(O)[C@@]5(CC3=C(COC(C)=O)C(=O)O4)[H])[H])[H])(CC7=C2[C@](C)([C@]8([C@@]7(C8)[H])[H])[C@@H](O)C1=O)[H])[H]