Vitexilactone
Product Specifications
CAS Number
61263-49-8
Target
Antifection|||NADPH-oxidase|||Apoptosis|||HIV Protease|||Antibacterial
Related Pathways
Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||Microbiology/Virology
Bioactivity
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal concentration against epimastigotes of Trypanosoma cruzi is 66 microM.Vitexilactone is one anticancer component of Vitex trifolia L., which exerts its anti-proliferative effect on cancer cells through inducing apoptosis and inhibiting the cell cycle.
Smiles
C[C@@H]1C[C@@H](OC(C)=O)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCC1=CC(=O)OC1
Molecular Formula
C22H34O5
Molecular Weight
378.509
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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