Tilifodiolide
Product Specifications
CAS Number
126724-95-6
Target
TNF, IL Receptor, GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience, Apoptosis, Immunology/Inflammation
Bioactivity
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
Smiles
O=C1OCC=C1[C@H]1CCc2ccc3C(=O)O[C@@H](c4ccoc4)c3c2C1
Molecular Formula
C20H16O5
Molecular Weight
336.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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