Tanshindiol C
Product Specifications
CAS Number
97465-71-9
Target
Sirtuin|||Nrf2|||LDL|||Histone Methyltransferase
Related Pathways
Immunology/Inflammation|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Metabolism
Bioactivity
Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors.
Smiles
Cc1coc-2c1C(=O)C(=O)c1c-2ccc2c1CC[C@@H](O)[C@]2(C)O
Molecular Formula
C18H16O5
Molecular Weight
312.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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