Skullcapflavone I
Product Specifications
CAS Number
41060-16-6
Target
Prostaglandin Receptor, IL Receptor, Caspase, MicroRNA, Serine Protease
Related Pathways
Proteases/Proteasome, Chromatin/Epigenetic, Immunology/Inflammation, GPCR/G Protein, Apoptosis
Bioactivity
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE (2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation.
Smiles
COc1cc(O)c2c(oc(cc2=O)-c2ccccc2O)c1OC
Molecular Formula
C17H14O6
Molecular Weight
314.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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